|
TEST |
USP |
EP / BP |
|
CHARACTERS |
------ |
A white, crystalline powder or colourless crystals, sublimes readily, slightly soluble in water, very soluble in alcohol, soluble in glycerol (85 per cent). |
|
IDENTIFICATION
|
A. Infrared absorption spectrum To comply
B. A yellowish precipitate of iodoform formed.
|
TEST A: The pyridine layer becomes red.
TEST B: A black precipitate is formed
TEST C: A yellowish precipitate is formed.
TEST D: It complies with the test for water
|
|
MELTING POINT |
----- |
It melts at about 78 °C, |
|
APPEARANCE OF SOLUTION |
----- |
To comply |
|
ACIDITY |
Shake thoroughly 0.5 g with 25 mL of water; the water remains neutral to litmus |
Not more than 1.0 ml of 0.01 M sodium hydroxide is required to change the colour of the indicator to blue |
|
CHLORIDE
|
NMT 0.07% |
NMT 100 ppm
|
|
WATER
|
NMT 6.0% |
4.5 per cent to 5.5 per cent |
|
SULPHATED ASH |
----- |
Not more than 0.1 per cent, |
|
ORGANIC VOLATILE IMPURITIES |
meets the requirements using G.C;
Chloroform: NMT 60 mcg/gm |
----- |
|
ASSAY |
98.0 to 100.5 % |
98.0 to 101.0 % |
